PROTAC
PROTACs are an innovative modality that removes disease-related proteins rather than simply inhibiting them. By recruiting the ubiquitin–proteasome system, PROTACs trigger targeted protein degradation for more complete therapeutic control.
E3Lingand
High-quality small molecules designed to bind specifically to the E3 Ubiquitin Ligase (such as Cereblon or VHL). This binding recruits the cellular machinery necessary for tagging the target protein.
E3 CRBN Ligand
